¡¾Major Papers of the Laboratory¡¿
?Oral dysbiosis and systemic diseases, FRONTIERS IN DENTAL MEDICINE, 3, 20220811
?Relationship Between Periodontitis and Atrial Fibrosis in Atrial Fibrillation Histological Evaluation of Left Atrial Appendages, JACC-CLINICAL ELECTROPHYSIOLOGY, 9(1), 43-53, 202301
?Mouse maternal odontogenic infection with Porphyromonas gingivalis induces cognitive decline in offspring, FRONTIERS IN PEDIATRICS, 11, 20230811
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Pathology is the study of the causes and mechanisms of diseases and aims to set standards for diagnosis to support the development of novel therapies. Our lectures provide a study of oral diseases and general diseases and their relationship to clinical application, which permit students to have a solid basis of dentistry.
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Our research activities are:
- By studying the mechanism of destruction and regeneration of periodontal tissues and missing links between periodontitis and systemic diseases, we focus on developing novel periodontal diagnostic examination and therapy.
- Developing a lactoferrin peptide drug for the control of bone-destroying diseases such as rheumatoid arthritis and periodontitis
- By determining the cellular differentiation of odontogenic and salivary gland tumors, we focus on setting criteria of pathological diagnosis of the tumors.
¡¾Figure 1¡¿ Mechanisms which periodontal pathogen; porphyromonas gingivalis promotes liver fibrosis
¡¾Figure 2¡¿ Elimination of odontogenic infection of porphyromonas gingivalis¡¡by dental treatment (DT) improved liver inflammation and fibrosis.£¨HFD£ºHigh fat diet feeding, P.g.: odontogenic infection, DT: dental treatment£©
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