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¡¾Major Papers of the Laboratory¡¿
?Broader adaptive range of sympathetic burst size in response to blood pressure change in older women with greater arterial stiffness, JOURNAL OF PHYSIOLOGY-LONDON, 598(16), 3331-3341, 202008
?Sympathetic Neural and Hemodynamic Responses During Cold Pressor Test in Elderly Blacks and Whites., Hypertension, 67(5), 951-958, 201605
?Asian women have attenuated sympathetic activation but enhanced renal-adrenal responses during pregnancy compared to Caucasian women., J Physiol, 593(5), 1159-1168, 201503

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Over a billion of people are living with some form of disability and chronic diseases, and still increasing due to population aging and improvements in medical technologies. Since the rate of adverse events associated with chromosome aberration and aging condition is not small, we learn to provide safe and high-quality dental services for them. Moreover, we can acquire ability to examine and elucidate underlying mechanisms of these problems.

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1. Evaluation of the circulatory systems in patients with cardiovascular and congenital heart diseases.
2. Effects of vasoconstrictor in local anesthesia on baroreflex sensitivity.
3. Relationship between central arterial stiffness and periodontal diseases, and the influence on baroreflex sensitivity.
4. Influences of sleep bruxism in hypoxia on the central cardiovascular control system.
5. Underlying mechanisms of suppressed pressor responses to pain stimulation by N2O.
6. Alterations of pulse wave reflection by sedative agents.
7. Effects of physical training on the oral immunofunction.